you would assume that as soon as the injected mRNA is consumed

I'm unaware of any papers investigating the life cycle of spike protein mRNA besides the biodistribution study that Dr. Bridle cites. This falls into the category of not being fully understood due to lack of long term data.

What he says make sense with the AZ and J&J vaccines, where you inject a vector... If what he is saying is true, you will have a much bigger problem with the vector based vaccines.

He is talking about Pfizer and Moderna in the interview. Vector vaccines such as AZ and J&J use adenovirus DNA that is disassembled in the nucleus, where the DNA is alternatively spliced to generate mRNA compatible with the host ribosomes where the SARS CoV-2 spike protein is translated. The alternative spicing allows for many spike mRNAs to be coded from a single gene. The end result of producing the spike protein to generate an immune response is the same, but as you say potentially more problematic due to volume of production.

Also, if the spike protein is a problem, imagine what happens to people that were infected with the virus...So in theory, a virus infection will cause a similar reaction

Dr. Bridle describes in the interview that certain symptoms of adverse reaction to the vaccine is consistent with certain symptoms of those suffering with Covid-19. "And doing that research what has been discovered by the scientific community is the spike protein on its own is almost entirely responsible for the damage to the cardiovascular system if it gets into circulation. Indeed if you inject the purified spike protein into the blood of research animals they get all kinds of damage to the cardiovascular system, it can cross the blood brain barrier and cause damage to the brain."