This is a beautiful example of social media misinformation. We have the speculations of a journalist with no medical background being presented as fact by some nameless troll.
So typical.
This MSM article by Allysia Finley with her BA in American Studies (https://www.wsj.com/news/author/allysia-finley) does not say - as V&C1 reports - that "the vaccinated are fueling the variants". She asks the question, and then uses a lot of words and some non-peer-reviewed documents to say "maybe".
She's just earning a paycheque. Gotta come up with something, I guess.
That’s a lot of useless feelings you shared Covid Nazi.
Perfect example of an uneducated Facebook posting Boomer sharing personal feelings about a scientific subject.
For those who pay attention to science and facts.
Bivalent vaccines only have two strains, the mRNA instructs the body to make Wuhan and BA.5 antibodies. In Darwinian terms, the virus learns how to imprint and evade so other antibodies win out—the booster makes the virus “fitter.”
XBB has evolved to elude mRNA antibodies and the vaccinated are getting more infected and more sick. Hence, the Nature study suggests, “current herd immunity and BA.5 vaccine boosters are not efficiently preventing the infection of Omicron convergent variants.” XXB covid infections and hospitalizations are the highest in the North East, where the bivalent 4th shot has the highest uptake.
The Cleveland Clinic study tracked its 51,011 healthcare workers and found that the bivalent vaccines failed to protect against BA.5 variant 70% of the time.
Notably, boosted healthcare workers who had received more doses were at higher risk of getting sick.
”The risk of COVID-19 infection varied by the number of COVID-19 vaccine doses previously received. The higher the number of vaccines previously received, the higher the risk of contracting COVID-19 (Figure 2)”.
It isn't. Vaccines exert evolutionary pressure favouring variants that escape vaccine induced antibodies. Whether or not that pressure results in an escape variant falls to chance but this chance is weighted. For example, say a variant has a geometric change brought about by different nucleotides in its spike but this change costs more to synthesize, this variant would be outcompeted in most situations. But say that more expensive sequence (less favourable enthalpy and entropy) happens to evade the antibody 90% of people have, well it has become incalculably more competitive and has an easier time passing between hosts.
Is it guaranteed to happen? No. Are there human created pressures favouring it? Yes.
Most people know how this works from paying some attention to antibiotic resistant bacteria. Same principle. Ubiquitous antibiotics applied evolutionary pressure. It took a long time but viruses get more rolls of the dice in less time.
This isn't even getting into the vaccinee's immune response to variants. If an antigen is similar to something you've encountered many times, the body tends to produce a best fit. Sort of. We're back to entropy and enthalpy. The path of least effort. If the body has thousands of flathead screwdrivers, it's going to try to screw in the Philips with a flathead instead of putting Philips heads into production. Unless something is so different that it doesn't register, such as a hexagonal screw.
The worry here is that a variant escapes enough to replicate relatively unhindered while highly boosted individuals are unable to mount a suitable response due to flooding the body with the answer to 2019's spike. The one we applied massive selectors against the existence of because we didn't restrict vaccines to comorbid and/or elderly groups. Presumably because Canada was greasing its way past human rights violations by mandating against everyone instead of singling out the people who needed it.
You are source trolling against basic evolutionary and life science principles. The ideas of epitopes, enzymes(catalysts), protein synthesis, erroneous transcription, viral stability VS replication errors AS WELL as the physics of thermodynamics (entropy and enthalpy) AND the mathematical idea of weighted causalities.
There's something called the 'Parachute Paradigm' to address people like you. It goes like this:
"This observation has come to be known as the parachute paradigm: We tend to accept the claim that parachutes reduce injury among people who leap from airplanes, but this effect has never been proved in a randomized study that compares an experimental parachute group to an unlucky parachuteless control".
You are dismissing long established theories, and in some case LAWS, because they haven't been repeated in a narrow context. It's akin to arguing that you might fall up instead of down when entering or exiting a newly designed vehicle. There could be confounding variables that might cause this or the appearance of it (wind tunnel? electromagnetism?) but we wouldn't retread the path and study it before the anomaly happened.
A highly mutable coronavirus stabilizing and never escaping the evolutionary pressure of ubiquitous vaccination that offers bloodborne resistance without mucosal resistance would be the anomaly. This is before getting into the pathology of COVID-19 where it fuses cells into multinucleated masses instead of lysing them which allows for more replication before detection. This is before considering animal reservoirs. And, of course, immunocompromised people who will get infected and allow for many more replication cycles (rolls of the dice) before the host immune system gets ahead of the infection. In these cases, the winning roll will be the one that alters the spike protein without crippling the virus's ability to enter cells to the point that it loses the race against the host's immune system.
I didn't mean to throw you off like that. It's an honest question: Can you say what the rate of variant production / survival would be without vaccines?
This is a beautiful example of social media misinformation. We have the speculations of a journalist with no medical background being presented as fact by some nameless troll.
So typical.
This MSM article by Allysia Finley with her BA in American Studies (https://www.wsj.com/news/author/allysia-finley) does not say - as V&C1 reports - that "the vaccinated are fueling the variants". She asks the question, and then uses a lot of words and some non-peer-reviewed documents to say "maybe".
She's just earning a paycheque. Gotta come up with something, I guess.
That’s a lot of useless feelings you shared Covid Nazi.
Perfect example of an uneducated Facebook posting Boomer sharing personal feelings about a scientific subject.
For those who pay attention to science and facts.
Making up quotes again, I guess.
Meanwhile your lady with the American studies BA has a few speculations and no peer-reviewed science to back them up.
But you're happy to pretend her guesses are proven science.
Like I say: typical medical misinformation from an anonymous troll on social media.
It isn't. Vaccines exert evolutionary pressure favouring variants that escape vaccine induced antibodies. Whether or not that pressure results in an escape variant falls to chance but this chance is weighted. For example, say a variant has a geometric change brought about by different nucleotides in its spike but this change costs more to synthesize, this variant would be outcompeted in most situations. But say that more expensive sequence (less favourable enthalpy and entropy) happens to evade the antibody 90% of people have, well it has become incalculably more competitive and has an easier time passing between hosts.
Is it guaranteed to happen? No. Are there human created pressures favouring it? Yes.
Most people know how this works from paying some attention to antibiotic resistant bacteria. Same principle. Ubiquitous antibiotics applied evolutionary pressure. It took a long time but viruses get more rolls of the dice in less time.
This isn't even getting into the vaccinee's immune response to variants. If an antigen is similar to something you've encountered many times, the body tends to produce a best fit. Sort of. We're back to entropy and enthalpy. The path of least effort. If the body has thousands of flathead screwdrivers, it's going to try to screw in the Philips with a flathead instead of putting Philips heads into production. Unless something is so different that it doesn't register, such as a hexagonal screw.
The worry here is that a variant escapes enough to replicate relatively unhindered while highly boosted individuals are unable to mount a suitable response due to flooding the body with the answer to 2019's spike. The one we applied massive selectors against the existence of because we didn't restrict vaccines to comorbid and/or elderly groups. Presumably because Canada was greasing its way past human rights violations by mandating against everyone instead of singling out the people who needed it.
Can you say what the rate of variant production / survival would be without vaccines?
You are source trolling against basic evolutionary and life science principles. The ideas of epitopes, enzymes(catalysts), protein synthesis, erroneous transcription, viral stability VS replication errors AS WELL as the physics of thermodynamics (entropy and enthalpy) AND the mathematical idea of weighted causalities.
There's something called the 'Parachute Paradigm' to address people like you. It goes like this:
"This observation has come to be known as the parachute paradigm: We tend to accept the claim that parachutes reduce injury among people who leap from airplanes, but this effect has never been proved in a randomized study that compares an experimental parachute group to an unlucky parachuteless control".
You are dismissing long established theories, and in some case LAWS, because they haven't been repeated in a narrow context. It's akin to arguing that you might fall up instead of down when entering or exiting a newly designed vehicle. There could be confounding variables that might cause this or the appearance of it (wind tunnel? electromagnetism?) but we wouldn't retread the path and study it before the anomaly happened.
A highly mutable coronavirus stabilizing and never escaping the evolutionary pressure of ubiquitous vaccination that offers bloodborne resistance without mucosal resistance would be the anomaly. This is before getting into the pathology of COVID-19 where it fuses cells into multinucleated masses instead of lysing them which allows for more replication before detection. This is before considering animal reservoirs. And, of course, immunocompromised people who will get infected and allow for many more replication cycles (rolls of the dice) before the host immune system gets ahead of the infection. In these cases, the winning roll will be the one that alters the spike protein without crippling the virus's ability to enter cells to the point that it loses the race against the host's immune system.
I didn't mean to throw you off like that. It's an honest question: Can you say what the rate of variant production / survival would be without vaccines?